Buy NadTime®

Yes, and that's exactly the science behind the formula. Research on NAD+ is today one of the most active areas in ageing biology: human studies show that maintaining optimal NAD+ levels is linked to better energy metabolism, greater cellular resilience and improved cognitive function with age. It's the scientific basis of what is known as longevity medicine.

NADTIME is formulated on that science. What we don't do is use "longevity" or "anti-ageing" as empty marketing promises, because COEUS's commitment is exactly the opposite: that every claim you read has behind it a formula, a registered ingredient and real evidence to support it.

Living longer and better isn't a slogan. It's the goal. And NADTIME is the nutritional architecture we work on every day to bring you closer to it.

NAD+ is a molecule present in all our cells that acts as the fuel they need to produce energy. Without enough NAD+, cells function worse: we get tired sooner, recover more slowly and think less clearly. Science has been researching how to maintain its levels with age for years, and the results are solid enough that it has stopped being an elite topic and become one of the most active areas of nutritional research worldwide.

Because rest repairs, but energy is manufactured. They're two different processes. The energy we use during the day is produced by mitochondria inside every cell, and to do so they need NAD+ and cofactors like B vitamins. When those levels drop — due to age, accumulated stress or high mental demand — we sleep the same hours but wake up without the energy we used to have. NADTIME works at that point: the cellular origin of fatigue, not the surface symptom.

Because over the years the body produces less NAD+, a molecule that cells need to generate energy. It's not a lack of willpower or rest: it's something that happens naturally and progressively in everyone. By age 60, we can have up to half the NAD+ we had at 20. That's why fatigue appears earlier, recovery takes longer and mental clarity decreases. NADTIME provides the nutrients involved in this process, and its B vitamins contribute to normal energy metabolism and the reduction of tiredness and fatigue according to European regulations.

Most supplements in this category work like this: they choose a single ingredient — NMN or NR — and build the entire product around it. They have studies to back them up and that's fine. But it's like trying to solve a complex problem with a single tool.

The decline of NAD+ with age doesn't have a single cause. It has three. The body produces less on its own. Enzymes like CD38 consume it faster. And oxidative stress accelerates that consumption even further. A single precursor only attacks the first front.

NADTIME works on all three at the same time. NAD+ LipoAvail® provides NAD+ protected in liposomal technology so it reaches where it needs to go. RiaGev® provides the precursors the body uses to manufacture its own NAD+ from the base. And quercetin, as a dietary antioxidant, contributes to reducing the oxidative stress that consumes it at an accelerated rate. On top of that, Quatrefolic® as the most active form of folate, vitamins B6 and B12 in forms the body can use directly, and choline as metabolic support.

NADTIME has four registered brand ingredients that work as a team:

NAD+ LipoAvail® — NAD+ encapsulated in liposomal technology that protects it during digestion and improves its stability until it reaches the cells. It's not generic NAD+: it's functionally available NAD+.

RiaGev® — Combines nicotinamide (a direct NAD+ precursor) and D-ribose (involved in the synthesis of energetic nucleotides). The body uses these nutrients to manufacture its own NAD+ from the metabolic base.

Quatrefolic® — The registered, active form of folic acid. It requires no prior metabolic conversion. Especially relevant for people with the MTHFR genetic variant, which hinders that conversion.

Quercetin 98% — A dietary flavonoid with antioxidant activity described in cellular studies. It contributes to reducing the oxidative stress that accelerates the consumption of NAD+ available for energy metabolism.

Additionally, vitamins B6 and B12 in active forms (P-5-P and methylcobalamin) and choline as additional metabolic support.

NADTIME is not a stimulant that acts in hours: it supports metabolic processes that work continuously and cumulatively. Most people with higher baseline fatigue levels notice changes in vitality and mental clarity between the second and fourth week of regular use. Results depend on each person's starting point, lifestyle and consistency of intake.

2 capsules in the morning, with water, alongside breakfast. In the morning because that's when the body starts its metabolic processes and makes better use of nutritional cofactors. With food because it improves digestive tolerance. Every day because consistency is what makes the difference in nutritional supplementation. Vegan, gluten-free, lactose-free and no added sugars.

Generally yes. The vitamin B6 in NADTIME provides 10.24 mg of active vitamin per daily dose, below the upper safety limit established by EFSA for adults. If you combine with other supplements containing vitamin B6, consult your pharmacist to avoid exceeding that limit. Not suitable for pregnant or breastfeeding women or minors. If you take regular medication, consult your doctor before starting.

For adults from 35-40 years onwards who notice their energy isn’t the same, who recover more slowly or who feel they perform below what they know they can give. For those who have read about NAD+, longevity or ageing biology and are looking for a formula with real scientific basis behind it. For those who want to do something concrete today for how they’ll feel tomorrow. Vegan, gluten-free, lactose-free and no added sugars.

The retail price is €39.90 per bottle (30 days at the recommended dose), which works out to €1.33 per day. With a monthly subscription you get a permanent 15% discount: €33.92/month, that’s €1.13 per day. Single-ingredient NMN or NR supplements range from €30-60 without liposomal technology, without antioxidants and with only one vector of action. NADTIME® works all three vectors of NAD+ decline simultaneously: NAD+ LipoAvail® for direct availability, RiaGev® for synthesis from the base, and quercetin to reduce oxidative consumption. The most complete cellular longevity formula in the COEUS catalogue. Vegan, gluten-free, lactose-free and no added sugars.

Pack Time combines RENEGEN®, NadTime® and Retromag® for adults from 40 onwards who want to invest in their cognition and cellular longevity over the long term. It’s the most longevity-focused pack in the range: RENEGEN® provides structural neuroprotection (Bacopa, Ginkgo, COGNIZIN®), NadTime® restores cellular energy metabolism via NAD+, and Retromag® maintains the mineral base for overnight repair.

It’s the pack that requires the most patience: Bacopa monnieri reaches its peak cognitive effect in clinical trials at 12 weeks. The minimum recommendation is 3 continuous months for real, sustained results. Protocol: RENEGEN® and NadTime® with breakfast; Retromag® at night.