Buy Renegen®

More than it seems. Brain ageing doesn't start at 70: it begins decades earlier, with silent changes in neuronal membranes, mitochondrial efficiency and methylation patterns that determine how neurotransmitters are synthesised and neuronal DNA is repaired.

The problem is that these processes don't hurt or show until the accumulated damage is significant. Advanced brain nutrition makes more sense at 35 than at 65, exactly like cardiovascular exercise.

RENEGEN® is formulated for those who want cognitive performance today and long-term brain reserve — without waiting for the first signs of decline. It's not a nootropic. It's not a multivitamin. It's the complete nutritional architecture of the brain: structure + flow + protection + methylation.

Taking care of the brain before it starts to fail isn't a slogan. It's the goal. And RENEGEN® is the nutritional architecture we work on every day to bring you closer to it.

A multivitamin corrects basic deficiencies. A stimulant nootropic gives a peak of activation followed by a crash. RENEGEN® does something different: it works on four simultaneous synergies that the other two cannot replicate.

The structural synergy with COGNIZIN® and phosphatidylserine optimises neuronal membranes and acetylcholine production. The functional synergy with bacopa and ginkgo supports memory, synaptic plasticity and cerebral blood flow. The epigenetic synergy with ALA, resveratrol and EGCG protects neuronal mitochondria from accumulated oxidative stress. And the methylation synergy with Quatrefolic®, active B12 and B6 P-5-P sustains neurotransmitter synthesis and DNA repair. No caffeine. No stimulants. No subsequent crash.

This is the most common profile of early functional cognitive decline: everything within normal ranges, but mental performance below expectations. It's not your imagination.

Standard blood tests don't measure neuronal membrane efficiency, acetylcholine production, methylation cycle status or mitochondrial oxidative load. Those are exactly the four fronts RENEGEN® works on. There is no single origin for this functional decline: that's why a single solution — a stimulant, a generic antioxidant, a basic B-complex — doesn't solve it. RENEGEN® works on all four simultaneously.

RENEGEN® has two clearly distinct usage profiles. The first is active performance: professionals or students with high cognitive demand who want to sustain focus and clarity under pressure without resorting to stimulants. The second is cognitive prevention: adults from 35-40 onwards who want to maintain their brain reserve before noticing the first changes.

It's not for those looking for a quick energy boost — RENERGY® exists in the catalogue for that. It's for those who want a solid cognitive base that improves over time. If you've been feeling for weeks that your mind doesn't respond like before, or if you simply want to care for your brain as you care for the rest, RENEGEN® is for this moment.

RENEGEN® works through four synergies designed to potentiate each other:

Structural synergy — COGNIZIN® (400 mg) + Phosphatidylserine 20% (200 mg). COGNIZIN® is the registered form of citicoline by Kyowa, with proprietary clinical studies in healthy adults. It provides choline for acetylcholine synthesis — the neurotransmitter of focus and working memory — and regenerates phosphatidylcholine in neuronal membranes. Phosphatidylserine optimises their fluidity and signalling efficiency between neurons.

Functional synergy — Bacopa monnieri 20% (300 mg) + Ginkgo biloba 24/6 (150 mg). Bacopa has meta-analyses in episodic memory and processing speed with the most robust effect from 8-12 weeks. Ginkgo improves cerebral microcirculation. The synergy is precise: ginkgo ensures nutrients arrive, bacopa uses them to strengthen synaptic connections.

Epigenetic synergy — ALA (150 mg) + Resveratrol 98% (50 mg) + EGCG green tea (100 mg) + Ferulic acid (50 mg). ALA activates AMPK and recycles endogenous antioxidants. Resveratrol activates SIRT1. EGCG enhances mitochondrial antioxidant protection. Ferulic acid stabilises resveratrol. Bioperine® improves the bioavailability of the whole formula.

Methylation synergy — Quatrefolic® B9 (400 mcg) + B12 Methylcobalamin (5 mcg) + B6 P-5-P (11.78 mg). Three ingredients in active forms that require no prior metabolic conversion. The methylation cycle they sustain is fundamental for serotonin and dopamine synthesis and neuronal myelin maintenance.

RENEGEN® has a progressive effect profile with three well-differentiated stages. In the first 2-4 weeks, greater subjective mental clarity and better focus during sustained cognitive effort are noticed — this is the effect of the structural block with COGNIZIN® and methylation support.

Between weeks 8 and 12, the improvement in memory and learning consolidates, which is the territory where bacopa has the strongest clinical evidence. The epigenetic and neuroprotective effect is the most cumulative and longest-lasting: it improves with continued use and has no ceiling effect. RENEGEN® is not a cycling product: it's for continued use, just like cognitive exercise.

It contains no caffeine or any other stimulant. The green tea included in the formula provides EGCG as an antioxidant and L-theanine as a modulator, not as a stimulant caffeine source. The recommendation is to take the two capsules with breakfast or lunch to optimise the absorption of fat-soluble ingredients.

It does not interfere with sleep. It is compatible with intermittent fasting protocols when taken during the eating window. Contains soy as a declared allergen.

In general, the safety profile is solid for adults without concomitant medication. There are relevant precautions: ginkgo biloba requires prior medical consultation if taking anticoagulants or antiplatelet agents due to its effect on platelet aggregation. Vitamin B6 at 841% NRV requires consultation if taking levodopa or other drugs with known B6 interaction.

ALA requires caution with chemotherapy treatments or thiamine deficiency. Not indicated for minors, pregnancy or breastfeeding. If you already take another supplement with COGNIZIN® or generic citicoline, consult your pharmacist to avoid duplicating the same mechanism.

The retail price is €44.90 per bottle (60 capsules, 30 days at 2 capsules/day). That's €1.50 per day for the only formula in Spanish pharmacies with COGNIZIN®, Quatrefolic® and Bioperine® in a four-synergy architecture without stimulants. With a monthly subscription you get a permanent 15% discount: €38.17/month, which works out to €1.27 per day.

Formulas with COGNIZIN® on the online market range from €35-55 without phosphatidylserine, without bacopa, without the epigenetic block or active methylation. RENEGEN® is complete coverage, not a single ingredient. Gluten-free, lactose-free, no added sugars. Contains soy.

RENEGEN® is designed for adults with high cognitive demand who want performance today and long-term brain reserve. Professionals, executives, students and anyone who has noticed their mind no longer responds as before, even though everything else is fine.

Within the COEUS catalogue, it combines especially well with NADTIME® for the 45+ profile focused on simultaneous brain and metabolic longevity. With RENERGY® for those with active daily cognitive fatigue. With RETROMAG® if muscle tension and compromised sleep limit underlying cognitive performance. And with RESCANSO® if night-time rest is the factor most limiting mental clarity.

Pack Biohack combines RENEGEN®, NadTime® and RENERGY® for simultaneous cognitive and mitochondrial optimisation. It's the most performance-oriented pack in the range for long-term mental performance: RENEGEN® provides structural neuroprotection, NadTime® optimises cellular metabolism via NAD+ and RENERGY® activates active daily mental performance.

It's not a pack for occasional use, but for those who prioritise cognitive health as a sustained investment. The three speeds of effect complement each other: RENERGY® from week one, NadTime® between weeks 2-6, RENEGEN® reaching its peak effect at 8-12 weeks. Protocol: all three products in the morning with breakfast. Adding Retromag® at night is recommended as a mineral recovery base.

2 capsules in the morning, with water, alongside breakfast. In the morning because the cognitive ingredients (Bacopa, Ginkgo, COGNIZIN®) deliver their effect during the hours of greatest mental demand. With food because it improves absorption and digestive tolerance. Every day, because Bacopa monnieri reaches its maximum cognitive effect in clinical trials at 12 weeks: consistency is key. Vegan, gluten-free, lactose-free and with no added sugars.